Chimerigen

Fc (human) IgG1 Control (rec.) (non-lytic)

As low as CHF 390.00

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CHI-HF-220IG1-C100100 µgCHF 390.00

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Product Details
Product Type	Protein
Properties
Source/Host	HEK 293 cells
Sequence	Human IgG Fc region (aa 100-330) containing the hinge sequence.
Crossreactivity	Human
MW	~25-35kDa (SDS-PAGE)
Purity	≥95% (SDS-PAGE)
Endotoxin Content	<1EU/mg purified protein (LAL test; Lonza).
Reconstitution	Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration.
Formulation	Lyophilized from 0.2μm-filtered solution in PBS.
Other Product Data	Non-lytic: Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Description

This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.

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