Chimerigen

Fc (mouse) IgG2a Control (rec.) (non-lytic)

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CHI-MF-120IG2A-C100100 µgCHF 390.00
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Product Details
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

Mouse IgG2a Fc region (aa 99-330) containing the hinge sequence.

Crossreactivity Mouse
MW ~26kDa (SDS-PAGE)
Purity ≥98% (SDS-PAGE)
Endotoxin Content <1EU/mg purified protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Other Product Data

Non-lytic: Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
After standard reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description

This product should be used as the control protein for activity tests of fusion proteins including mouse target proteins and mouse IgG2a-Fc domains.

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